ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,676, issued on July 21, was assigned to ALCHEMEDICINE INC. (Ibaraki, Japan).

"Compound, endothelin-A receptor antagonist, and pharmaceutical composition" was invented by Keigo Tanaka (Tsukuba, Japan), Tomohisa Ninomiya (Tsukuba, Japan) and Yoshihide Tomata (Tsukuba, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "An object of the present invention is to provide a compound having an ETA receptor antagonistic effect, etc. The object can be attained by a compound represented by the following formula (1):wherein variables are as described herein, or a pharmaceutically acceptable salt thereof."

The patent was filed on June 21, 2022, under Applicati...