US Patent Issued to ALBERT-LUDWIGS-UNIVERSITAT FREIBURG on Aug. 25 for "Rescue of recombinant adenoviruses by CRISPR/Cas-mediated in vivo terminal resolution" (German Inventors)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,716,064, issued on Aug. 25, was assigned to ALBERT-LUDWIGS-UNIVERSITAT FREIBURG (Freiburg, Germany).

"Rescue of recombinant adenoviruses by CRISPR/Cas-mediated in vivo terminal resolution" was invented by Zsolt Ruzsics (DieBen am Ammersee, Germany), Andre Riedl (Schweitenkirchen, Germany), Julian Fischer (Freiburg, Germany) and Hans-Gerhard Burgert (Bad Krozingen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to circular DNA molecule for rescuing recombinant adenoviruses comprising a recombinant adenoviral genome with two inverted terminal repeats (ITRs) flanking the genome ends, wherein at least one of the ITRs is associa...