ALEXANDRIA, Va., June 12 -- United States Patent no. 12,298,308, issued on May 13, was assigned to Albert Einstein College of Medicine (Bronx, N.Y.).
"Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism" was invented by John S. Condeelis (Bronx, N.Y.) and Maja Oktay (Rye, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using Tie-2 inhibitors. Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using inhibitors of Mena expression and/or fun...