ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,755, issued on Jan. 27, was assigned to Agilent Technologies Inc. (Santa Clara, Calif.).
"Compositions and methods for performing hybridizations with separate denaturation of the sample and probe" was invented by Steen Hauge Matthiesen (Hillerod, Denmark).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides methods and compositions for separately denaturing a probe and target in hybridization applications. The invention may, for example, eliminate the use of, or reduce the dependence on formamide in hybridization applications. Compositions for use in the invention include an aqueous composition comprising at least one polar aprotic s...