US Patent Issued to Agency for Science, Technology and Research on June 23 for "Heterocyclic compounds as modulators of beta-catenin / TCF4 interaction" (Singaporean Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,661,338, issued on June 23, was assigned to Agency for Science, Technology and Research (Singapore).

"Heterocyclic compounds as modulators of beta-catenin / TCF4 interaction" was invented by Joo Leng Low (Singapore), Weina Du (Singapore), Ramanuj Dasgupta (Singapore), Hao Fan (Singapore) and Tenzin Gocha (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds that are useful for or methods of inhibiting Beta-catenin or disrupting the interaction between Beta-catenin and T-cell factor 4, which are useful in the treatment of diseases or health conditions, such as cancer, neurodegenerative, a metabolic disease, a cardiovascu...