US Patent Issued to Agency for Science, Technology and Research, National University of Singapore on March 17 for "Microglia-sufficient brain organoids" (Singaporean Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,531, issued on March 17, was assigned to Agency for Science, Technology and Research (Singapore) and National University of Singapore (Singapore).

"Microglia-sufficient brain organoids" was invented by Dong Shin Park (Singapore), Florent Ginhoux (Singapore), Mahmoud Pouladi (Singapore) and Jinqiu Zhang (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for generating a microglia-sufficient brain organoid comprising the step of incubating primitive-like macrophage cells with a brain organoid that is between about 15 to about 30 days old in cerebral organoid medium comprising CSF-1 in a low attachment cell culture vessel to generate m...