ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,734,136, issued on Sept. 15, was assigned to Afyx Development A/S (Horsholm, Denmark).

"Intranasal administration of ketamine to cluster headache patients" was invented by Per Holm (Vanlose, Denmark), Ole Pedersen (Smorum, Denmark) and John Claude Krusz (Dallas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a method of treating patients with Cluster Headache (CH) including chronic Cluster Headache (cCH) comprising intranasal administration to a patient in need thereof of an aqueous composition, e.g., pharmaceutical composition, comprising a therapeutically effective amount of ketamine, which may reduce or eliminate side effects of ketamine ...