ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,751,928, issued on Oct. 6, was assigned to ADVICENNE (Paris).

"Prolonged-release pharmaceutical composition for oral administration of sultiame" was invented by Caroline Roussel-Maupetit (St-Ismier, France), Catherine Guittet (Arles, France) and Alexandra Guillermin (Grenoble, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a prolonged-release pharmaceutical composition for oral administration of sultiame in the form of particles wherein the amount of sultiame is from 0.5 mg to 5.0 mg per particle, and the particles have a particle size of less than 5000 micro metre and comprise an outer layer providing prolonged-re...