ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,176, issued on Sept. 8, was assigned to ACTINIUM PHARMACEUTICALS INC. (New York).
"Compositions and methods of immunodepletion for the treatment of malignant and non-malignant hematological diseases" was invented by Dale L. Ludwig (Rockaway, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention provides a method for depleting a subject's hematopoietic stem cells that includes administering to the subject an effective amount of a radiolabeled antibody against CD34, CD117, or CD135, where preferred radiolabels include 131I and 225Ac. This invention also provides a method for treating a subject afflicted with a non-cancerous disorder treat...