ALEXANDRIA, Va., Feb. 24 -- United States Patent no. RE50,805, issued on Feb. 24, was assigned to ACADIA Pharmaceuticals Inc. (San Diego).

"Single-layer oral dose of neuro-attenuating ketamine" was invented by Alex Nivorozhkin (West Roxbury, Mass.) and Nelson Landrau (Marlborough, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to oral neuro-attenuating ketamine (NAKET) tablet formulations, and methods of administration, which ensure the steady release of a therapeutically effective concentration of ketamine from an oral tablet without neurologically toxic spikes in ketamine concentration. In particular, the present invention provides single layer oral tablet formulatio...