US Patent Issued to ACADEMIA SINICA on June 23 for "Enterovirus 71 mutations associated with disease severity" (Taiwanese, American Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,711, issued on June 23, was assigned to ACADEMIA SINICA (Taipei, Taiwan).

"Enterovirus 71 mutations associated with disease severity" was invented by Chiaho Shih (Houston), Chun-Che Liao (Taipei, Taiwan) and Chih-Shin Chang (Taipei, Taiwan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of detecting severe disease-associated mutations in an enterovirus 71 (EV-A71), comprising: performing an assay on a test sample containing an EV-A71 genomic RNA, a fragment thereof or an amplicon thereof, or an EV-A71 VP1 protein or fragment thereof to detect one or more severe disease-associated mutations in the EV-A71 genomic RNA, the fragment thereof or t...