US Patent Issued to 10x Genomics on July 21 for "Compositions, systems and methods for CRISPR-based enzyme optimization" (California Inventor)

ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,884, issued on July 21, was assigned to 10x Genomics Inc. (Pleasanton, Calif.).

"Compositions, systems and methods for CRISPR-based enzyme optimization" was invented by Michael Gibbons (Pleasanton, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are reaction mixtures, compositions, systems, methods, and kits for assessing enzymatic activity. Aspects of the disclosure include use of a reactant barcoded oligonucleotide (RBO) construct comprising a first oligonucleotide comprising a reaction barcode sequence and a first linker that connects the first oligonucleotide to a first reactant, an amplification construct comprising a seco...