ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,949, issued on Feb. 10, was assigned to 10x Genomics Inc. (Pleasanton, Calif.).
"Resolving spatial arrays using deconvolution" was invented by Zachary Bent (Pleasanton, Calif.), Eswar Prasad Ramachandran Iyer (Sunnyvale, Calif.) and Tarjei Sigurd Mikkelsen (Pleasanton, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for determining a location of a feature on a spatial array include (a) providing an array of features on a substrate, where a feature of the array includes a barcoded oligonucleotide having, in a 5' to 3' direction, a spatial barcode, a cleavage domain, and a constant sequence; (b) hybridizing a priming oligonucleotide to t...