US Patent Issued to 10X GENOMICS on Aug. 11 for "RNase H assisted in situ rolling circle amplification" (California Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,879, issued on Aug. 11, was assigned to 10X GENOMICS INC. (Pleasanton, Calif.).

"RNase H assisted in situ rolling circle amplification" was invented by Yufeng Qian (Pleasanton, Calif.) and Shankar Shastry (Pleasanton, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates in some aspects to methods for analyzing a target RNA in a biological sample, such as detection of a sequence of interest in an RNA. In some aspects, provided herein are methods of using an RNase such as RNase H to provide in situ RNA detection methods having high sensitivity, efficiency, and/or specificity."

The patent was filed on March 28, 2023, un...