ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,103, issued on Sept. 8.

"Pharmaceutical composition comprising mitotane administered orally for treatment of adrenocortical carcinoma and Cushing's syndrome" was invented by Mohamed Skiba (Montmain, France), Malika Lahiani-Skiba (Montmain, France), Frederic Bounoure (Bois Guillaume, France), Michael Thomas (Mont-Saint-Aignan, France) and Herve Lefebvre (N-D de Bondeville, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "An object of the present invention is the preparation and use of a new dry emulsion (DE) containing mitotane and its use for the oral route for the treatment of adrenocortical carcinoma, congenital adrenal hyperplasia and Cushin...