US Patent Issued on Sept. 8 for "Enhanced peptide constructs for albumin binding" (New Jersey Inventor)

ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,222, issued on Sept. 8.

"Enhanced peptide constructs for albumin binding" was invented by Michael Farber (Livingston, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A synthetic peptide construct comprises an amino acid sequence-RLIEDICLPRWGCLWEDD (SEQ ID NO: 2) (also known as "GLYCLOK"), a flexible, hydrophilic glycine-serine (Gly-Ser) linker, and a polypeptide chain between 25 to 70 amino acids in length, which incorporates an albumin-binding moiety with a dissociation constant (Kd) to albumin of less than 20 nanomolar (nM). This construct may include the sequence RLIEDICLPRWGCLWEDD (SEQ. ID NO: 2) within its terminal 25 amino acids. The album...