ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,734,140, issued on Sept. 15.

"Methods for treating bone and neuropathic pain with capsaicin" was invented by James Ciullo (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "A transdermal patch and methods for delivering capsaicin to reduce pain are disclosed. The patch comprises capsaicin and a release liner, and may include permeation-enhancing agents. High-dose patches are configured for short-duration application to produce localized defunctionalization of TRPV1-expressing nociceptive terminals, while low-dose patches provide sustained delivery for extended wear. Application to affected dermatomes or regions of sensory loss reduces pain associa...