ALEXANDRIA, Va., May 26 -- United States Patent no. 12,636,329, issued on May 26.

"Recombinant oncolytic virus, preparation method therefor, use thereof and medicine thereof" was invented by Zetang Wu (Anhui, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are an oncolytic virus, a preparation method therefor, the use thereof and a medicine thereof, wherein the genome of the oncolytic virus includes the following exogenous elements: (1) a first expression cassette containing a first promoter and a first interfering RNA expression sequence; (2) a target sequence; and (3) a second expression cassette. The replication of the oncolytic virus is regulated and controlled by exogenous elements inserte...