US Patent Issued on May 12 for "HLA-DR/CII peptide complexes for treating arthritis" (German, Swedish Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,622,946, issued on May 12.

"HLA-DR/CII peptide complexes for treating arthritis" was invented by Nhu-Nguyen Do (Langen, Germany), Vilma Urbonaviciute (Spanga, Sweden), Sylvia Cienciala (Nidderau, Germany), Rikard Holmdahl (Stockholm) and Harald Burkhardt (Frankfurt am Main, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to HLA-DR/CII peptide complexes comprising a chondroitin-binding peptide at the C-terminal end of the polypeptide comprising the HLA-DR/CII alpha chain and/or the HLA-DR/CII beta chain, wherein the CII peptide is fused to the N-terminus of the HLA-DR/CII alpha chain or the HLA-DR/CII beta chain by a l...