ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,329, issued on March 31.
"Replicase cycling reaction (RCR)" was invented by Shi-Lung Lin (Arcadia, Calif.), Sam Lin (Arcadia, Calif.) and Chun-Hung Lin (Taipei, Taiwan).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention generally relates to a novel RNA/mRNA production and amplification method using viral RNA replicase and/or RNA-dependent RNA polymerase (RdRp) enzymes as well as the associated mRNAs thereof. The present invention can be used for manufacturing and amplifying all varieties of RNA/mRNA sequences carrying at least an RdRp-binding site in the 5'- or 3'-end, or both. The RNA/mRNA so obtained is useful for not only producing mRN...