US Patent Issued on June 16 for "Systems, methods, and compositions for targeted nucleic acid editing" (Massachusetts Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,655,403, issued on June 16.

"Systems, methods, and compositions for targeted nucleic acid editing" was invented by Feng Zhang (Cambridge, Mass.), Jonathan Gootenberg (Cambridge, Mass.), David Benjamin Turitz Cox (Cambridge, Mass.), Omar Abudayyeh (Cambridge, Mass.) and Ian Slaymaker (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the present disclosure provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Cas13 protein, at least one guide molecule, and at least one adeno...