ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,618, issued on July 15.
"Rapamycin (RAPA) self-microemulsifying injection and preparation method and use thereof" was invented by Pengke Yan (Guangzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "A rapamycin (RAPA) self-microemulsifying injection includes a drug stock solution and a diluent. The drug stock solution includes a drug solvent, an antioxidant, and RAPA, and the diluent includes a surfactant and water. RAPA is dissolved in the drug solvent. After the stock solution is diluted with the diluent, the solution is self-assembled into a microemulsion under the action of a surfactant, and RAPA is encapsulated in the microemulsion, whic...