US Patent Issued on Feb. 10 for "Compositions and methods of use for secretoglobins to protect the glycocalyx via interactions with heparan sulfate proteoglycan proteins" (Maryland Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,424, issued on Feb. 10.

"Compositions and methods of use for secretoglobins to protect the glycocalyx via interactions with heparan sulfate proteoglycan proteins" was invented by Aprile L. Pilon-Clayton (Rockville, Md.) and Melissa E. Winn (Rockville, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "SCGB-based preparations and methods to use these preparations to protect the glycocalyx in medical, veterinary, and cosmetic applications are provided. The secretoglobins (SCGBs) are a family of small secreted globular proteins present in all mammals and sharing conserved structure and thought to share similar immunomodulatory functions. Heparan sulfat...