ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,721, issued on Aug. 11.

"Conformationally stabilized RSV pre-fusion F proteins" was invented by Christopher Marshall (New York), Mark Yondola (New York), Roberto Mariani (New York), Aaron Zomback (Cheshire, Conn.) and Sonal Gidwani (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, ...