ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,830, issued on April 21.
"Protected antibody-drug and aptamer-drug conjugates" was invented by Kenneth Michael Kosak (Salt Lake City) and Matthew Kenneth Kosak (Corona, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention is a new strategy using a rational design for a "flexible" drug carrier composition, meaning that it provides drug release with a conformational change under specific conditions. Said carrier in its "closed" conformation, contains a drug wherein significant release of Said drug from its carrier only occurs during or after said conformational change, such as when a ligand binding domain is removed. Said carrier can ...