US Patent Issued on April 14 for "MRNA induced expression of bone morphogenic protein and receptor and methods related thereto" (Ohio Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,990, issued on April 14.

"MRNA induced expression of bone morphogenic protein and receptor and methods related thereto" was invented by Alexander Day (Cleveland) and Bradford Mullin (New Albany, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and treatments including preparing a synthetic messenger ribonucleic acid (mRNA) encoding at least for a bone morphogenic protein (BMP) and/or a BMP receptor. The synthetic mRNA is lipid-solubilized in a lipid or lipid derivative carrier. Intraoperatively, a bone harvest sample is obtained and incubated with the lipid-solubilized mRNA. The bone harvest sample internalizes at least a portion of the ...