Geneva, March 23 -- International Clinical Trials Registry received information related to the study (NCT07468136) titled 'Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas' on March 9.

Study Type: Interventional

Study Design: Allocation: Randomized. Intervention model: Sequential Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: Mayo Clinic

Condition: Anaplastic Oligodendroglioma Astrocytoma, IDH-Mutant, Grade 3 Astrocytoma, IDH-Mutant, Grade 4 Diffuse Astrocytoma Glioblastoma, IDH-Wildtype Malignant Glioma

Intervention: Procedure: Biospecimen Collection Drug: Eflornithine Procedure: Lumbar Puncture Procedure: Magnetic Resonance Imaging Biol...