International Clinical Trial: Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

Geneva, April 20 -- International Clinical Trials Registry received information related to the study (NCT07513389) titled 'Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)' on April 1.

Study Type: Interventional

Study Design: Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: Medical University of South Carolina

Condition: Squamous Cell Carcinoma Human Papilloma Virus (HPV) Oropharyngeal Squamous Cell Carcinoma (OPSCC)

Intervention: Other: Active Surveillance With ctHPVDNA (NavDx(R))

Recruitment Status: Not recruiting

Phase: Phase 2

Date of First Enrollment: July 1, 2026

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