Geneva, Sept. 21 -- International Clinical Trials Registry received information related to the study (ChiCTR2600131551) titled 'Furmonertinib Dose-Escalation Plus Bevacizumab with VP Shunt and Intrathecal Pemetrexed in EGFR-Mutant NSCLC with Leptomeningeal Metastases: A Phase II Study' on Sept. 3.

Study Type: Interventional study

Study Design: Single arm

Primary Sponsor: Shanghai Pulmonary Hospital

Condition: patients with EGFR-mutant non-small cell lung cancer and leptomeningeal metastases

Recruitment Status: Not Recruiting

Phase: 4

Date of First Enrollment: 2026-10-01

Target Sample Size: Treatment group receiving dose-escalated furmonertinib combined with bevacizumab, ventriculoperitoneal shunt and intrathecal pemetrexed:27...