HUMAN LUNG ORGANOIDS WITH A BUILT-IN IMMUNE SYSTEM COULD TRANSFORM RESPIRATORY DISEASE RESEARCH

BETHESDA, Md., Oct. 7 -- The U.S. Department of Health & Human Services' National Institutes of Health issued the following press release:

A new organoid model built with human lung fragments may help us answer key questions about one of the body's first lines of defense against respiratory pathogens. In a National Institutes of Health (NIH)-supported study, researchers at the Stanford University School of Medicine elicited virus-specific immune responses from these organoids and showed that administering a virus booster weakened subsequent infections.

The findings suggest the lung mucosa's immune system alone may provide significant protection, which adds to growing evidence that vaccination strategies designed to train up the body's fr...