U.S., June 5 -- ClinicalTrials.gov registry received information related to the study (NCT07627256) titled 'Weight Loss Composition and Metabolic Adaptation During Hypocaloric Dieting' on May 31.
Brief Summary: Weight loss induced by hypocaloric dietary interventions is commonly accompanied by reductions in resting metabolic rate (RMR), a phenomenon often described as metabolic adaptation. The magnitude of this decline varies substantially between individuals and may depend not only on the amount of weight lost but also on the composition of weight loss, particularly the relative contributions of fat mass and fat-free mass.
This prospective interventional study will investigate whether changes in body composition during a hypocaloric diet...