Clinical Trial: Vancomycin Efficacy in Response to Dysbiosis in Atypical Colitis

U.S., June 13 -- ClinicalTrials.gov registry received information related to the study (NCT07646223) titled 'Vancomycin Efficacy in Response to Dysbiosis in Atypical Colitis' on June 04.

Brief Summary: The goal of this clinical trial is to learn how oral vancomycin therapy may contribute in treating paediatric inflammatory bowel disease, particularly atypical ulcerative colitis and PSC-associated colitis. It will also give more information on how this treatment affects gut microbiota and metabolism.

The main questions it aims to answer are:

1. Does oral vancomycin improve disease activity and lead to remission (based on symptoms, biomarkers, and endoscopy findings)?

2. How does oral vancomycin change gut metabolism?

3. Does different t...