Clinical Trial: Vaginal Platelet-Rich Plasma and Vaginal Histology in Genitourinary Syndrome of Menopause

U.S., Oct. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07905820) titled 'Vaginal Platelet-Rich Plasma and Vaginal Histology in Genitourinary Syndrome of Menopause' on Oct. 23.

Brief Summary: This study evaluates whether subepithelial injection of autologous platelet-rich plasma (PRP) into the vaginal wall produces histological changes consistent with tissue regeneration in postmenopausal women with genitourinary syndrome of menopause (GSM). Women with GSM and concomitant pelvic organ prolapse who were scheduled for reconstructive prolapse surgery received two treatment sessions four weeks apart. Within each participant, three predefined vaginal regions received PRP injection, normal saline injection or n...