U.S., April 4 -- ClinicalTrials.gov registry received information related to the study (NCT07510776) titled 'UP STUDY - Decipher Persistent Critical Illness Through in Deep Clinical Phenotyping.' on Dec. 03, 2025.
Brief Summary: Persistent Critical Illness (PCI) is a condition that affects some patients who remain in the Intensive Care Unit (ICU) for a long time, usually more than 10-14 days. It is estimated to occur in 5-20% of critically ill patients. A recent Portuguese study found that more than 14% of ICU patients stayed longer than 14 days. PCI is often associated with ongoing need for life support, such as mechanical ventilation or medications to maintain blood pressure. However, patients may also experience severe muscle weakness, ...