U.S., Oct. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07883148) titled 'TPSAlz - Transcranial Pulse Stimulation in Alzheimer's Disease' on March 26, 2025.

Brief Summary: The goal of this study is to evaluate the effects of transcranial pulse stimulation (TPS) in modulating cognitive functions as well as structural and functional connectivity in individuals with mild cognitive impairment and early Alzheimer's disease. The main outcome measure is to confirm whether TPS may be considered as an effective treatment to improve memory in a large cohort of participants and investigating its long-term effects. Then, secondary measurements are to evaluate if TPS may induce neuronal connectivity changes and may co...