Clinical Trial: Topical Calcipotriol Versus Photodynamic Therapy in the Treatment of Oral Leukoplakia

U.S., June 23 -- ClinicalTrials.gov registry received information related to the study (NCT07658508) titled 'Topical Calcipotriol Versus Photodynamic Therapy in the Treatment of Oral Leukoplakia' on June 03.

Brief Summary: The goal of this clinical trial is to learn if calcipotriol and photodynamic therapy are equally effective in treatment of leukoplakia or not. The main questions it aims to answer are:

do lesions decrease or disappear when treated by calcipotriol or PDT? does the drug affect the salivary biomarkers

Participants will:

Take calcipotriol daily for 4 weeks or perform 4 PDT sessions over 4 weeks measure changes in salivary biomarkers be followed up for 3 months

Study Start Date: July 16, 2025

Study Type: INTERVENTIONAL ...