U.S., Aug. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07771426) titled 'The SPARK-PMDD Study' on Aug. 11.

Brief Summary: Scientists have found that the immune system, the body's system dedicated to fighting infections, can be in a state of "hyperactivity" (i.e., more active than you would normally expect) in some people with depression and postnatal depression, despite the lack of any actual ongoing infection. This response is referred to as inflammation. This discovery has unveiled unique opportunities to identify new medications to help patients with this heightened inflammation who have also not been responding to their antidepressant medications.

This study aims to explore how inflammation in the b...