U.S., Sept. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07835269) titled 'The PERK Study: Predicting and Evaluating Response to Knee RFA Using fNIRS' on Sept. 17.

Brief Summary: The goal of this clinical trial is to understand whether changes in brain activity, measured using functional near-infrared spectroscopy (fNIRS), are related to how well patients with knee osteoarthritis respond to genicular nerve radiofrequency ablation (GNRFA). The main questions it aims to answer are:

1. Are baseline brain activation patterns measured using fNIRS associated with clinically meaningful treatment responses to GNRFA?

2. What changes in brain activation patterns do we see overtime after GNRFA in those who are res...