U.S., March 12 -- ClinicalTrials.gov registry received information related to the study (NCT07463495) titled 'The Metabolic Effects of Oral Tributyrin Administration' on March 05.
Brief Summary: The goal of this double-blinded randomized clinical cross-over trial is to investigate the metabolic and appetite regulating effects of oral tributyrin (a butyrate pro-drug) administration vs placebo.
The main questions it aims to answer are:
* Does tributyrin have glucose lowering properties in humans?
* Does tributyrin reduce appetite in humans?
A sample size calculation estimated a minimum of 10 participants. We expect to include 12 participants in this study. Tributyrin or placebo is ingested once or twice daily for 2x2 weeks, separated by ...