U.S., Sept. 13 -- ClinicalTrials.gov registry received information related to the study (NCT07171320) titled 'The Efficacy and Safety of Pregabalin Combined With Desvenlafaxine in Patients With Fibromyalgia' on Sept. 07.
Brief Summary: Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters. The current mainstream treatments include pregabalin, but the efficacy of pregabalin is limited, with only 25%-40% pain relief rate, and adverse reactions are common. Selective serotonin and norepinephrine reuptake inhibitors (SNRIs), such as duloxetine and venlafaxine, have demonstrated efficacy in F...