U.S., Nov. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07935044) titled 'The Analgesic Effects of Chest Orthosis Application in Costal Fractures' on Jan. 29, 2025.
Brief Summary: Rib fractures are a common cause of acute pain after blunt chest trauma. In the emergency department, pain is usually managed with a multimodal approach including nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, local anesthetic sprays, patches and nerve blocks. Systemic analgesics may cause gastrointestinal, renal and hepatic adverse effects, and opioids carry the risk of respiratory depression and dependence. External chest wall stabilization with a rib orthosis may reduce pain by stabilizing the fracture with fewer sys...