Clinical Trial: Targeting Immune Modulation in High Grade Serous Carcinoma: Combined Effects of Chemotherapy and Atorvastatin

U.S., Sept. 12 -- ClinicalTrials.gov registry received information related to the study (NCT07815704) titled 'Targeting Immune Modulation in High Grade Serous Carcinoma: Combined Effects of Chemotherapy and Atorvastatin' on Aug. 31.

Brief Summary: The goal of this clinical trial is to learn how atorvastatin in patients with advanced high grade serous cancer of the ovary, fallopian tube, or peritoneum changes the tumor immune environment. The main question it aims to answer is:

* Does atorvastatin combined with standard of care chemotherapy and surgery changes the number of tumor-promoting macrophages in the tumor microenvironment

* Researchers will compare standard of care chemotherapy and surgery to see if there is a difference in tumor...