Clinical Trial: Study of Correlation Between the Level of Intradiscal Periostin Expression and Pfirrmann Grading.

U.S., Aug. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07776366) titled 'Study of Correlation Between the Level of Intradiscal Periostin Expression and Pfirrmann Grading.' on Aug. 17.

Brief Summary: Intervertebral disc degeneration (IVDD) is a well-recognized musculoskeletal condition that imposes a substantial socioeconomic burden and is an important cause of low back pain. IVDD can result from a variety of factors, including aging, obesity, genetic predisposition, degeneration of the multifidus and psoas muscles, osteoporosis, inflammation, and oxidative stress. The intervertebral disc (IVD) within the spine is composed of a gel-like nucleus pulposus (NP) at its center, a surrounding annulus fibrosus (...