Clinical Trial: Study Comparing Limited and Extensive Neck Surgery in Oral Cancer Patients With Neck Spread

U.S., July 22 -- ClinicalTrials.gov registry received information related to the study (NCT07717307) titled 'Study Comparing Limited and Extensive Neck Surgery in Oral Cancer Patients With Neck Spread' on July 11.

Brief Summary: Oral cavity squamous cell carcinoma (OCSCC) frequently metastasizes to cervical lymph nodes, and the extent of neck dissection remains an area of ongoing debate in patients with clinically node-positive (cN1) disease. While modified neck dissection (MND, levels I-V) is widely practiced, selective neck dissection (SND, levels I-IV) may provide equivalent oncologic outcomes with reduced surgical morbidity. However, high-quality randomized evidence comparing these approaches is lacking.

The ExteNT N1 Trial is a prosp...