Clinical Trial: Safety and Efficacy Study of Novel Gene Therapy AGX-08 for Geographic Atrophy

U.S., May 23 -- ClinicalTrials.gov registry received information related to the study (NCT07602127) titled 'Safety and Efficacy Study of Novel Gene Therapy AGX-08 for Geographic Atrophy' on May 17.

Brief Summary: This is AGX-08's safety, tolerability, and efficacy in Geographic Atrophy first-in-human study. This trial is meant to evaluate the safety and efficacy of AGX-08 in Geographic Atrophy patients. Unilateral intravitreal injections (IVT) will be given into the subject's Study Eye.

Study Start Date: July 01

Study Type: INTERVENTIONAL

Condition: Geographic Atrophy

Intervention: DRUG: AGX-08-L

rAAV2.AG-eNCRV intravitreal injection of low dose

DRUG: AGX-08-M

rAAV2.AG-eNCRV intravitreal injection of middle dose

DRUG: AGX-08-H

r...