Clinical Trial: Safety, Efficacy and Cellular Metabolic Dynamics of CT1195E in Patients With Refractory / Progressive SSC

U.S., Jan. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07355972) titled 'Safety, Efficacy and Cellular Metabolic Dynamics of CT1195E in Patients With Refractory / Progressive SSC' on Nov. 19, 2025.

Brief Summary: This study is a single arm, open label, exploratory dose escalation clinical study to evaluate the safety, efficacy, and cellular metabolic dynamics of ct1195e cells in patients with SSc.

The study was divided into dose escalation phase and dose expansion phase.

Study Start Date: Jan. 16

Study Type: INTERVENTIONAL

Condition: SSc-Systemic Sclerosis

Intervention: OTHER: CAR-T Therapy

CT1195E cells infusion

Recruitment Status: RECRUITING

Sponsor: Union Hospital, Tongji Medical College, Hu...