U.S., March 7 -- ClinicalTrials.gov registry received information related to the study (NCT07454252) titled 'Retrospective Monocentric Evaluation of Biomarkers Associated With Bone, Muscle and Energy Metabolism' on Sept. 05, 2025.
Brief Summary: Bone is a metabolically active tissue undergoing continuous remodeling through the coordinated actions of osteoclasts (resorption), osteoblasts (formation), and osteocytes (regulation). Under physiological conditions, bone formation and resorption are balanced and regulated by systemic hormones (PTH, vitamin D, estrogens) and local mediators. However, aging, metabolic disorders, physical inactivity, or pharmacological treatments may disrupt this equilibrium, leading to the predominance of one proce...