U.S., Aug. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07777575) titled 'Resistance Training to Prevent Muscle Loss During Treatment With Tirzepatide' on Aug. 17.
Brief Summary: Incretin-based pharmacotherapies induce significant weight loss and represent a paradigm shift in obesity treatment. However, particularly fast weight loss may be accompanied by a significant loss of muscle mass, which is associated with a reduced metabolic rate at rest and during physical activity, increased insulin resistance, limited mobility, and potential long-term adverse effects. The aim of this clinical trial is to examine the effects of resistance training versus standard of care on contractile thigh muscle volume in pat...