Clinical Trial: Repurposing a Combination Antiretroviral Drug Therapy to Target Retrotransposons and Treat Early Alzheimer's Disease

U.S., Sept. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07795307) titled 'Repurposing a Combination Antiretroviral Drug Therapy to Target Retrotransposons and Treat Early Alzheimer's Disease' on Aug. 24.

Brief Summary: The goal of this clinical trial is to determine the safety, tolerability, drug levels and biological effects of two doses of emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF) combination administered daily for 4 weeks in older adults with early Alzheimer's disease. The main questions it aims to answer are:

* Is FTC-TDF combination safe in older adults who have early Alzheimer's disease.

* To measure the FTC-TDF levels at different times.

* To measure the biological effects of F...