Clinical Trial: Prophylactic Radiotherapy to Prevent Bone Complications in Patients With Metastatic Solid Cancers

U.S., April 21 -- ClinicalTrials.gov registry received information related to the study (NCT07540650) titled 'Prophylactic Radiotherapy to Prevent Bone Complications in Patients With Metastatic Solid Cancers' on April 02.

Brief Summary: This is a prospective, randomized, single-center clinical trial evaluating whether early prophylactic radiotherapy to high-risk asymptomatic or minimally symptomatic bone metastases reduces the 1-year rate of skeletal-related events (SREs) in patients with metastatic solid cancers. Patients will be randomized in a 1:1 ratio to receive either standard of care systemic therapy or observation, or prophylactic radiotherapy in addition to standard of care. The primary endpoint is the 1-year rate of SREs. Seconda...